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Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence

Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of efflux systems, which is mostly unexplored. In this...

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Detalles Bibliográficos
Autores principales:	Machado, Diana, Lecorche, Emmanuel, Mougari, Faiza, Cambau, Emmanuelle, Viveiros, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300501/ https://www.ncbi.nlm.nih.gov/pubmed/30619157 http://dx.doi.org/10.3389/fmicb.2018.03072

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