Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis

Cancer-derived exosomes are considered a major driver of cancer-induced pre-metastatic niche formation at foreign sites, but the mechanisms remain unclear. Here, we show that miR-25-3p, a metastasis-promoting miRNA of colorectal cancer (CRC), can be transferred from CRC cells to endothelial cells vi...

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Detalles Bibliográficos
Autores principales: Zeng, Zhicheng, Li, Yuling, Pan, Yangjian, Lan, Xiaoliang, Song, Fuyao, Sun, Jingbo, Zhou, Kun, Liu, Xiaolong, Ren, Xiaoli, Wang, Feifei, Hu, Jinlong, Zhu, Xiaohui, Yang, Wei, Liao, Wenting, Li, Guoxin, Ding, Yanqing, Liang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300604/
https://www.ncbi.nlm.nih.gov/pubmed/30568162
http://dx.doi.org/10.1038/s41467-018-07810-w

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