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Nintedanib inhibits TGF-β-induced myofibroblast transdifferentiation in human Tenon’s fibroblasts
PURPOSE: This study aimed to investigate the effect of nintedanib on the conversion of human Tenon’s fibroblasts (HTFs) into myofibroblasts and reveal the molecular mechanisms involved. METHODS: Primary cultured HTFs were incubated with transforming growth factor β1 (TGF-β1) alone or combined with n...
Autores principales: | Lin, Xianchai, Wen, Jiamin, Liu, Rongjiao, Gao, Wuyou, Qu, Bo, Yu, Minbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300612/ https://www.ncbi.nlm.nih.gov/pubmed/30636861 |
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