Integrin CD11b activation drives anti-tumor innate immunity

Myeloid cells are recruited to damaged tissues where they can resolve infections and tumor growth or stimulate wound healing and tumor progression. Recruitment of these cells is regulated by integrins, a family of adhesion receptors that includes integrin CD11b. Here we report that, unexpectedly, in...

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Detalles Bibliográficos
Autores principales: Schmid, Michael C., Khan, Samia Q., Kaneda, Megan M., Pathria, Paulina, Shepard, Ryan, Louis, Tiani L., Anand, Sudarshan, Woo, Gyunghwi, Leem, Chris, Faridi, M. Hafeez, Geraghty, Terese, Rajagopalan, Anugraha, Gupta, Seema, Ahmed, Mansoor, Vazquez-Padron, Roberto I., Cheresh, David A., Gupta, Vineet, Varner, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300665/
https://www.ncbi.nlm.nih.gov/pubmed/30568188
http://dx.doi.org/10.1038/s41467-018-07387-4

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