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Development of an Opsonophagocytic Killing Assay Using HL-60 Cells for Detection of Functional Antibodies against Streptococcus pyogenes

The clinical development of group A streptococcal (GAS) vaccines will require the implementation of a standardized, high-throughput assay to measure the activity of functional opsonic antibodies in vaccine recipients. In the present study, we adapted and modified the HL-60-based protocol that was de...

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Detalles Bibliográficos
Autores principales:	Salehi, Sanaz, Hohn, Claudia M., Penfound, Thomas A., Dale, James B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300688/ https://www.ncbi.nlm.nih.gov/pubmed/30567901 http://dx.doi.org/10.1128/mSphere.00617-18

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