Saccharomyces cerevisiae morphological changes and cytokinesis arrest elicited by hypoxia during scale-up for production of therapeutic recombinant proteins

BACKGROUND: Scaling up of bioprocesses represents a crucial step in the industrial production of biologicals. However, our knowledge about the impact of scale-up on the organism’s physiology and function is still incomplete. Our previous studies have suggested the existence of morphological changes...

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Detalles Bibliográficos
Autores principales: Aon, Juan C., Tecson, Ricardo C., Loladze, Vakhtang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300885/
https://www.ncbi.nlm.nih.gov/pubmed/30572885
http://dx.doi.org/10.1186/s12934-018-1044-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300885/
https://www.ncbi.nlm.nih.gov/pubmed/30572885
http://dx.doi.org/10.1186/s12934-018-1044-2

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