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Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population

OBJECTIVE: We evaluated the role of rotation thromboelastometry (ROTEM) in managing acute traumatic coagulopathy in pediatric patients with trauma. METHODS: A retrospective cohort of pediatric patients with trauma from six institutes was studied during a 10-year period from 2007 to 2017. The associa...

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Autores principales: Deng, Qin, Hao, Fabao, Wang, Yongming, Guo, Chunbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300942/
https://www.ncbi.nlm.nih.gov/pubmed/30200794
http://dx.doi.org/10.1177/0300060518794092
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author Deng, Qin
Hao, Fabao
Wang, Yongming
Guo, Chunbao
author_facet Deng, Qin
Hao, Fabao
Wang, Yongming
Guo, Chunbao
author_sort Deng, Qin
collection PubMed
description OBJECTIVE: We evaluated the role of rotation thromboelastometry (ROTEM) in managing acute traumatic coagulopathy in pediatric patients with trauma. METHODS: A retrospective cohort of pediatric patients with trauma from six institutes was studied during a 10-year period from 2007 to 2017. The associations between ROTEM-guided, goal-directed coagulation therapy and clinical outcomes were determined. RESULTS: Three hundred thirty-two pediatric patients (age < 15 years) who were treated with ROTEM-guided, goal-directed coagulation therapy were matched to 332 control pediatric patients with conventional plasmatic coagulation tests. The ROTEM protocol was associated with a significant reduction in the interval for admission to acute traumatic coagulopathy treatment, less plasma transfusions in the first 24 hours of admission, and a favorable coagulopathy recovery. Furthermore, the median number of total hospital days was significantly shorter for patients who had the ROTEM protocol than for control patients. CONCLUSIONS: There are significant favorable outcomes, including rapid acute traumatic coagulopathy treatment and a lower 24-hour blood product requirement, following ROTEM-guided, goal-directed coagulation therapy among pediatric patients with blunt trauma.
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spelling pubmed-63009422019-01-11 Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population Deng, Qin Hao, Fabao Wang, Yongming Guo, Chunbao J Int Med Res Clinical Research Reports OBJECTIVE: We evaluated the role of rotation thromboelastometry (ROTEM) in managing acute traumatic coagulopathy in pediatric patients with trauma. METHODS: A retrospective cohort of pediatric patients with trauma from six institutes was studied during a 10-year period from 2007 to 2017. The associations between ROTEM-guided, goal-directed coagulation therapy and clinical outcomes were determined. RESULTS: Three hundred thirty-two pediatric patients (age < 15 years) who were treated with ROTEM-guided, goal-directed coagulation therapy were matched to 332 control pediatric patients with conventional plasmatic coagulation tests. The ROTEM protocol was associated with a significant reduction in the interval for admission to acute traumatic coagulopathy treatment, less plasma transfusions in the first 24 hours of admission, and a favorable coagulopathy recovery. Furthermore, the median number of total hospital days was significantly shorter for patients who had the ROTEM protocol than for control patients. CONCLUSIONS: There are significant favorable outcomes, including rapid acute traumatic coagulopathy treatment and a lower 24-hour blood product requirement, following ROTEM-guided, goal-directed coagulation therapy among pediatric patients with blunt trauma. SAGE Publications 2018-09-10 2018-12 /pmc/articles/PMC6300942/ /pubmed/30200794 http://dx.doi.org/10.1177/0300060518794092 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Research Reports
Deng, Qin
Hao, Fabao
Wang, Yongming
Guo, Chunbao
Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population
title Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population
title_full Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population
title_fullStr Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population
title_full_unstemmed Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population
title_short Rotation thromboelastometry (ROTEM) enables improved outcomes in the pediatric trauma population
title_sort rotation thromboelastometry (rotem) enables improved outcomes in the pediatric trauma population
topic Clinical Research Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300942/
https://www.ncbi.nlm.nih.gov/pubmed/30200794
http://dx.doi.org/10.1177/0300060518794092
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