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Management and prognosis of cancers in the accessory parotid gland

OBJECTIVE: This study was performed to analyze the clinical management of accessory parotid gland (APG) cancer and possible risk factors for disease-related death. METHODS: Patients diagnosed with primary APG cancers in the largest medical center in Northeast China were enrolled from January 1990 to...

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Autores principales: Han, Xiaoxue, Zhang, Xifeng, Gao, Yuqin, Pang, Pai, Liu, Fayu, Sun, Changfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300960/
https://www.ncbi.nlm.nih.gov/pubmed/30289052
http://dx.doi.org/10.1177/0300060518767792
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author Han, Xiaoxue
Zhang, Xifeng
Gao, Yuqin
Pang, Pai
Liu, Fayu
Sun, Changfu
author_facet Han, Xiaoxue
Zhang, Xifeng
Gao, Yuqin
Pang, Pai
Liu, Fayu
Sun, Changfu
author_sort Han, Xiaoxue
collection PubMed
description OBJECTIVE: This study was performed to analyze the clinical management of accessory parotid gland (APG) cancer and possible risk factors for disease-related death. METHODS: Patients diagnosed with primary APG cancers in the largest medical center in Northeast China were enrolled from January 1990 to December 2016. RESULTS: All 43 patients underwent resection of the tumors and superficial parotid gland by a standard Blair incision. Seven (16.3%) patients also required selective neck dissection. The most common lesion was mucoepidermoid carcinoma. Temporary facial paralysis occurred in 11 (25.6%) patients, and permanent facial paralysis occurred in 3 (7.0%) patients because of surgical resection of the facial nerve, which was involved with the tumor. The 5- and 10-year disease-specific survival rates were 86.0% and 66.0%, respectively. The tumor stage, neck status, neck dissection, and tumor grade were significantly associated with disease-related death, but only the tumor grade was an independent risk factor. CONCLUSION: Superficial parotidectomy is a reliable surgical procedure associated with a high survival rate and low morbidity in treating APG cancers. The tumor grade is the key prognostic factor.
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spelling pubmed-63009602019-01-11 Management and prognosis of cancers in the accessory parotid gland Han, Xiaoxue Zhang, Xifeng Gao, Yuqin Pang, Pai Liu, Fayu Sun, Changfu J Int Med Res Clinical Research Reports OBJECTIVE: This study was performed to analyze the clinical management of accessory parotid gland (APG) cancer and possible risk factors for disease-related death. METHODS: Patients diagnosed with primary APG cancers in the largest medical center in Northeast China were enrolled from January 1990 to December 2016. RESULTS: All 43 patients underwent resection of the tumors and superficial parotid gland by a standard Blair incision. Seven (16.3%) patients also required selective neck dissection. The most common lesion was mucoepidermoid carcinoma. Temporary facial paralysis occurred in 11 (25.6%) patients, and permanent facial paralysis occurred in 3 (7.0%) patients because of surgical resection of the facial nerve, which was involved with the tumor. The 5- and 10-year disease-specific survival rates were 86.0% and 66.0%, respectively. The tumor stage, neck status, neck dissection, and tumor grade were significantly associated with disease-related death, but only the tumor grade was an independent risk factor. CONCLUSION: Superficial parotidectomy is a reliable surgical procedure associated with a high survival rate and low morbidity in treating APG cancers. The tumor grade is the key prognostic factor. SAGE Publications 2018-10-05 2018-12 /pmc/articles/PMC6300960/ /pubmed/30289052 http://dx.doi.org/10.1177/0300060518767792 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Research Reports
Han, Xiaoxue
Zhang, Xifeng
Gao, Yuqin
Pang, Pai
Liu, Fayu
Sun, Changfu
Management and prognosis of cancers in the accessory parotid gland
title Management and prognosis of cancers in the accessory parotid gland
title_full Management and prognosis of cancers in the accessory parotid gland
title_fullStr Management and prognosis of cancers in the accessory parotid gland
title_full_unstemmed Management and prognosis of cancers in the accessory parotid gland
title_short Management and prognosis of cancers in the accessory parotid gland
title_sort management and prognosis of cancers in the accessory parotid gland
topic Clinical Research Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300960/
https://www.ncbi.nlm.nih.gov/pubmed/30289052
http://dx.doi.org/10.1177/0300060518767792
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