miR-106a deficiency attenuates inflammation in murine IBD models.

Pro-inflammatory cytokine TNFα antagonizes regulatory T cell (Treg) suppressive function with a measurable reduction of IL-10 protein secretion. Tregs are critical to suppress excessive immune activation, particularly within the intestine where high antigenic loads elicit chronic subclinical immune...

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Detalles Bibliográficos
Autores principales: Sanctuary, Megan R., Huang, Rick H., Jones, Ashleigh A., Luck, Marisa E., Aherne, Carol M., Jedlicka, Paul, de Zoeten, Edwin F., Collins, Colm B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301105/
https://www.ncbi.nlm.nih.gov/pubmed/30327532
http://dx.doi.org/10.1038/s41385-018-0091-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301105/
https://www.ncbi.nlm.nih.gov/pubmed/30327532
http://dx.doi.org/10.1038/s41385-018-0091-7

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