Defective IgA response to atypical intestinal commensals in IL-21 receptor deficiency reshapes immune cell homeostasis and mucosal immunity

Despite studies indicating the effects of IL-21 signaling in intestinal inflammation, its roles in intestinal homeostasis and infection are not yet clear. Here, we report potent effects of commensal microbiota on the phenotypic manifestations of IL-21 receptor deficiency. IL-21 is produced highly in...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Hyeseon, Jaime, Henrique, Oliveira, Rafael Pires, Kang, Byunghyun, Spolski, Rosanne, Vaziri, Tina, Myers, Timothy G., Thovarai, Vishal, Shen, Zeli, Fox, James G., Leonard, Warren J., Kelsall, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301133/
https://www.ncbi.nlm.nih.gov/pubmed/30087442
http://dx.doi.org/10.1038/s41385-018-0056-x

Ejemplares similares

Ejemplares similares