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Screening of the Pathogen Box reveals new starting points for anti-trypanosomal drug discovery

This study aimed to uncover new starting points for anti-trypansomal drug discovery through the screening of the Pathogen Box against Trypanosoma brucei brucei. Our study identified compounds 35, 39, 46, 53 and 56 whose activity and selectivity highlighted them as promising candidates with potential...

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Detalles Bibliográficos
Autores principales: Veale, Clinton G. L., Hoppe, Heinrich C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301270/
https://www.ncbi.nlm.nih.gov/pubmed/30647879
http://dx.doi.org/10.1039/c8md00319j