Macrophage expression of E3 ubiquitin ligase Grail protects mice from lipopolysaccharide-induced hyperinflammation and organ injury

Multiple organ dysfunction caused by hyperinflammation remains the major cause of mortality during sepsis. Excessive M1-macrophage activation leads to systemic inflammatory responses. Gene related to anergy in lymphocytes (Grail) is regarded as an important regulator of T cells that functions by dim...

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Detalles Bibliográficos
Autores principales: Shih, Chih-Chin, Liu, Pei-Yao, Chen, Jye-Hann, Liao, Mei-Hui, Hsieh, Chih-Ming, Ka, Shuk-Man, Wu, Chin-Chen, Lin, Hui-Tsu, Wu, Ti-Hui, Chen, Ying-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301572/
https://www.ncbi.nlm.nih.gov/pubmed/30571701
http://dx.doi.org/10.1371/journal.pone.0208279

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