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Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance

A practical method was designed to verify the accuracy of dose distributions calculated using Compass, which can reconstruct the dose distribution inside a patient’s body during intensity-modulated radiation therapy (IMRT). Twelve virtual IMRT treatment plans were developed using an ArcCHECK diode d...

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Detalles Bibliográficos
Autores principales: Song, Ju-Young, Ahn, Sung-Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301628/
https://www.ncbi.nlm.nih.gov/pubmed/30571796
http://dx.doi.org/10.1371/journal.pone.0209180
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author Song, Ju-Young
Ahn, Sung-Ja
author_facet Song, Ju-Young
Ahn, Sung-Ja
author_sort Song, Ju-Young
collection PubMed
description A practical method was designed to verify the accuracy of dose distributions calculated using Compass, which can reconstruct the dose distribution inside a patient’s body during intensity-modulated radiation therapy (IMRT). Twelve virtual IMRT treatment plans were developed using an ArcCHECK diode detector array, and then the recalculated and reconstructed doses in Compass were compared with the actual measurements to assess the dosimetric accuracy. Based on the results of gamma evaluation for the 12 plans, Compass achieved average pass rates higher than 98%, which confirmed proper dosimetric accuracy in the IMRT quality assurance process. The validity of Compass for clinical applications was also confirmed through an additional comparison with the results calculated using 3DVH, another dose reconstruction program. It is necessary to verify the accuracy of the dose calculated using the program in advance before the commercialized dose reconstruction program is applied in clinical practice. This study has limitations in that it did not provide a real scientific contribution such as an introduction of new algorithm for dose calculation and the development of new measurement tools. However, the method based on the comparative analysis with the actual measured dose values as devised in this study seems to be useful in that it can be applied effectively to verify the dosimetric accuracy of the dose reconstruction program before first using it in the clinical cases.
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spelling pubmed-63016282019-01-08 Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance Song, Ju-Young Ahn, Sung-Ja PLoS One Research Article A practical method was designed to verify the accuracy of dose distributions calculated using Compass, which can reconstruct the dose distribution inside a patient’s body during intensity-modulated radiation therapy (IMRT). Twelve virtual IMRT treatment plans were developed using an ArcCHECK diode detector array, and then the recalculated and reconstructed doses in Compass were compared with the actual measurements to assess the dosimetric accuracy. Based on the results of gamma evaluation for the 12 plans, Compass achieved average pass rates higher than 98%, which confirmed proper dosimetric accuracy in the IMRT quality assurance process. The validity of Compass for clinical applications was also confirmed through an additional comparison with the results calculated using 3DVH, another dose reconstruction program. It is necessary to verify the accuracy of the dose calculated using the program in advance before the commercialized dose reconstruction program is applied in clinical practice. This study has limitations in that it did not provide a real scientific contribution such as an introduction of new algorithm for dose calculation and the development of new measurement tools. However, the method based on the comparative analysis with the actual measured dose values as devised in this study seems to be useful in that it can be applied effectively to verify the dosimetric accuracy of the dose reconstruction program before first using it in the clinical cases. Public Library of Science 2018-12-20 /pmc/articles/PMC6301628/ /pubmed/30571796 http://dx.doi.org/10.1371/journal.pone.0209180 Text en © 2018 Song, Ahn http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Song, Ju-Young
Ahn, Sung-Ja
Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance
title Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance
title_full Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance
title_fullStr Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance
title_full_unstemmed Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance
title_short Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance
title_sort dosimetric evaluation of the compass program for patient dose analysis in imrt delivery quality assurance
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301628/
https://www.ncbi.nlm.nih.gov/pubmed/30571796
http://dx.doi.org/10.1371/journal.pone.0209180
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