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Protective effects of voltage-gated calcium channel antagonists against zinc toxicity in SN56 neuroblastoma cholinergic cells
One of the pathological site effects in excitotoxic activation is Zn(2+) overload to postsynaptic neurons. Such an effect is considered to be equivalent to the glutamate component of excitotoxicity. Excessive uptake of Zn(2+) by active voltage-dependent transport systems in these neurons may lead to...
Autores principales: | Zyśk, Marlena, Gapys, Beata, Ronowska, Anna, Gul-Hinc, Sylwia, Erlandsson, Anna, Iwanicki, Adam, Sakowicz-Burkiewicz, Monika, Szutowicz, Andrzej, Bielarczyk, Hanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301650/ https://www.ncbi.nlm.nih.gov/pubmed/30571745 http://dx.doi.org/10.1371/journal.pone.0209363 |
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