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Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis

A crucial step in cell differentiation is the silencing of developmental programs underlying multipotency. While much is known about how lineage-specific genes are activated to generate distinct cell types, the mechanisms driving suppression of stemness are far less understood. To address this, we e...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Debadrita, Rothstein, Megan, Azambuja, Ana Paula, Simoes-Costa, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301792/
https://www.ncbi.nlm.nih.gov/pubmed/30520734
http://dx.doi.org/10.7554/eLife.40556