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Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis
A crucial step in cell differentiation is the silencing of developmental programs underlying multipotency. While much is known about how lineage-specific genes are activated to generate distinct cell types, the mechanisms driving suppression of stemness are far less understood. To address this, we e...
Autores principales: | Bhattacharya, Debadrita, Rothstein, Megan, Azambuja, Ana Paula, Simoes-Costa, Marcos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301792/ https://www.ncbi.nlm.nih.gov/pubmed/30520734 http://dx.doi.org/10.7554/eLife.40556 |
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