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Sorafenib inhibits caspase-1 expression through suppressing TLR4/stat3/SUMO1 pathway in hepatocellular carcinoma
Sorafenib has been demonstrated to be a beneficial treatment for advanced hepatocellular carcinoma (HCC). Emerging evidence indicates that caspase-1 activation plays a crucial role in HCC progression. However, the relationship between caspase-1 and sorafenib has rarely been reported. In this study,...
Autores principales: | Li, Jun, Zhou, Yuan, Liu, Yang, Dai, Bo, Zhang, Yu-Hen, Zhang, Peng-Fei, Shi, Xiao-Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301813/ https://www.ncbi.nlm.nih.gov/pubmed/30277836 http://dx.doi.org/10.1080/15384047.2018.1480280 |
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