Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer

Pediatric high grade gliomas (HGG) are primary brain malignancies that result in significant morbidity and mortality. One of the challenges in their treatment is inter- and intra-tumoral heterogeneity. Precision medicine approaches have the potential to enhance diagnostic, prognostic and/or therapeu...

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Detalles Bibliográficos
Autores principales: Tsoli, Maria, Wadham, Carol, Pinese, Mark, Failes, Tim, Joshi, Swapna, Mould, Emily, Yin, Julia X., Gayevskiy, Velimir, Kumar, Amit, Kaplan, Warren, Ekert, Paul G., Saletta, Federica, Franshaw, Laura, Liu, Jie, Gifford, Andrew, Weber, Martin A., Rodriguez, Michael, Cohn, Richard J., Arndt, Greg, Tyrrell, Vanessa, Haber, Michelle, Trahair, Toby, Marshall, Glenn M., McDonald, Kerrie, Cowley, Mark J., Ziegler, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Bedside to Bench Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301829/
https://www.ncbi.nlm.nih.gov/pubmed/30299205
http://dx.doi.org/10.1080/15384047.2018.1491498

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