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Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty

Purpose  The purpose of the present study was to assess perception of pain and pain management in smokers versus nonsmokers who received a total hip arthroplasty (THA). Methods  Patients who underwent THA from 2010 to 2016 were propensity score matched 1:1 based on race, body mass index, age, and se...

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Autores principales: Etcheson, Jennifer I., Gwam, Chukwuweike U., George, Nicole E., Walia, Naval, Jerjian, Christophe, Han, Ga-ram, Virani, Sana, Miller, Seth J., Delanois, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301853/
https://www.ncbi.nlm.nih.gov/pubmed/30582103
http://dx.doi.org/10.1055/s-0038-1673405
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author Etcheson, Jennifer I.
Gwam, Chukwuweike U.
George, Nicole E.
Walia, Naval
Jerjian, Christophe
Han, Ga-ram
Virani, Sana
Miller, Seth J.
Delanois, Ronald E.
author_facet Etcheson, Jennifer I.
Gwam, Chukwuweike U.
George, Nicole E.
Walia, Naval
Jerjian, Christophe
Han, Ga-ram
Virani, Sana
Miller, Seth J.
Delanois, Ronald E.
author_sort Etcheson, Jennifer I.
collection PubMed
description Purpose  The purpose of the present study was to assess perception of pain and pain management in smokers versus nonsmokers who received a total hip arthroplasty (THA). Methods  Patients who underwent THA from 2010 to 2016 were propensity score matched 1:1 based on race, body mass index, age, and sex. This yielded 124 smokers and 124 nonsmokers. Pain intensity was quantified using area under the curve for visual analog scale pain scores. Opioid consumption was determined using a morphine milliequivalent (mEq) conversion algorithm. An independent samples t -test and Chi-square analysis was conducted to assess continuous and categorical variables respectively. Results  Smokers experienced a nonsignificantly increased pain intensity (198.1 vs. 185.7; p  = 0.063). Smokers demonstrated significantly higher opioid consumption in both immediate postoperative (65.9 vs. 59.3 mEq; p  = 0.045) and 90 days postoperative periods (619.9 vs. 458.9 mEq; p  = 0.029). Conclusion  Our study demonstrated a nonsignificantly increased pain intensity, and (in both the immediate and 90 days postoperative periods) a significantly higher opioid consumption following THA in patients who smoke cigarettes. This may be due to a relatively small effect size, warranting the need for larger prospective studies. Nevertheless, arthroplasty surgeons should encourage preoperative smoking cessation and alternative nonopioid analgesics to smoking patients receiving THA. Level of Evidence  This is a level III, retrospective cohort study.
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spelling pubmed-63018532018-12-21 Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty Etcheson, Jennifer I. Gwam, Chukwuweike U. George, Nicole E. Walia, Naval Jerjian, Christophe Han, Ga-ram Virani, Sana Miller, Seth J. Delanois, Ronald E. Joints Purpose  The purpose of the present study was to assess perception of pain and pain management in smokers versus nonsmokers who received a total hip arthroplasty (THA). Methods  Patients who underwent THA from 2010 to 2016 were propensity score matched 1:1 based on race, body mass index, age, and sex. This yielded 124 smokers and 124 nonsmokers. Pain intensity was quantified using area under the curve for visual analog scale pain scores. Opioid consumption was determined using a morphine milliequivalent (mEq) conversion algorithm. An independent samples t -test and Chi-square analysis was conducted to assess continuous and categorical variables respectively. Results  Smokers experienced a nonsignificantly increased pain intensity (198.1 vs. 185.7; p  = 0.063). Smokers demonstrated significantly higher opioid consumption in both immediate postoperative (65.9 vs. 59.3 mEq; p  = 0.045) and 90 days postoperative periods (619.9 vs. 458.9 mEq; p  = 0.029). Conclusion  Our study demonstrated a nonsignificantly increased pain intensity, and (in both the immediate and 90 days postoperative periods) a significantly higher opioid consumption following THA in patients who smoke cigarettes. This may be due to a relatively small effect size, warranting the need for larger prospective studies. Nevertheless, arthroplasty surgeons should encourage preoperative smoking cessation and alternative nonopioid analgesics to smoking patients receiving THA. Level of Evidence  This is a level III, retrospective cohort study. Georg Thieme Verlag KG 2018-10-18 /pmc/articles/PMC6301853/ /pubmed/30582103 http://dx.doi.org/10.1055/s-0038-1673405 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Etcheson, Jennifer I.
Gwam, Chukwuweike U.
George, Nicole E.
Walia, Naval
Jerjian, Christophe
Han, Ga-ram
Virani, Sana
Miller, Seth J.
Delanois, Ronald E.
Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty
title Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty
title_full Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty
title_fullStr Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty
title_full_unstemmed Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty
title_short Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty
title_sort opiate pain medication consumption in cigarette smokers following total hip arthroplasty
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301853/
https://www.ncbi.nlm.nih.gov/pubmed/30582103
http://dx.doi.org/10.1055/s-0038-1673405
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