Cargando…

Different pro-angiogenic potential of γ-irradiated PBMC-derived secretome and its subfractions

Secretomes from various cell sources exert strong regenerative activities on numerous organs, including the skin. Although secretomes consist of many diverse components, a growing body of evidence suggests that small extracellular vesicles (EVs) account for their regenerative capacity. We previously...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wagner, Tanja, Traxler, Denise, Simader, Elisabeth, Beer, Lucian, Narzt, Marie-Sophie, Gruber, Florian, Madlener, Sibylle, Laggner, Maria, Erb, Michael, Vorstandlechner, Vera, Gugerell, Alfred, Radtke, Christine, Gnecchi, Massimiliano, Peterbauer, Anja, Gschwandtner, Maria, Tschachler, Erwin, Keibl, Claudia, Slezak, Paul, Ankersmit, Hendrik J., Mildner, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301954/ https://www.ncbi.nlm.nih.gov/pubmed/30573762 http://dx.doi.org/10.1038/s41598-018-36928-6

Ejemplares similares

Tissue-regenerative potential of the secretome of γ-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis
por: Simader, Elisabeth, et al.
Publicado: (2019)

Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products
por: Laggner, Maria, et al.
Publicado: (2020)

Therapeutic potential of lipids obtained from γ-irradiated PBMCs in dendritic cell-mediated skin inflammation
por: Laggner, Maria, et al.
Publicado: (2020)

Comparing the efficacy of γ- and electron-irradiation of PBMCs to promote secretion of paracrine, regenerative factors
por: Laggner, Maria, et al.
Publicado: (2021)

The secretome of irradiated peripheral blood mononuclear cells attenuates activation of mast cells and basophils
por: Laggner, Maria, et al.
Publicado: (2022)

Analysis of the Secretome of Apoptotic Peripheral Blood Mononuclear Cells: Impact of Released Proteins and Exosomes for Tissue Regeneration
por: Beer, Lucian, et al.
Publicado: (2015)

Safety and tolerability of topically administered autologous, apoptotic PBMC secretome (APOSEC) in dermal wounds: a randomized Phase 1 trial (MARSYAS I)
por: Simader, Elisabeth, et al.
Publicado: (2017)

Toxicological testing of allogeneic secretome derived from peripheral mononuclear cells (APOSEC): a novel cell-free therapeutic agent in skin disease
por: Wuschko, Silvio, et al.
Publicado: (2019)

The secretome of stressed peripheral blood mononuclear cells increases tissue survival in a rodent epigastric flap model
por: Hacker, Stefan, et al.
Publicado: (2020)

The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
por: Vorstandlechner, Vera, et al.
Publicado: (2023)

Secretome of Peripheral Blood Mononuclear Cells Enhances Wound Healing
por: Mildner, Michael, et al.
Publicado: (2013)

Safety and clinical efficacy of the secretome of stressed peripheral blood mononuclear cells in patients with diabetic foot ulcer—study protocol of the randomized, placebo-controlled, double-blind, multicenter, international phase II clinical trial MARSYAS II
por: Gugerell, Alfred, et al.
Publicado: (2021)

The serine proteases dipeptidyl-peptidase 4 and urokinase are key molecules in human and mouse scar formation
por: Vorstandlechner, Vera, et al.
Publicado: (2021)

The transcriptional profile of keloidal Schwann cells
por: Direder, Martin, et al.
Publicado: (2022)

Dying blood mononuclear cell secretome exerts antimicrobial activity
por: Kasiri, Mohammad Mahdi, et al.
Publicado: (2016)

TGF-β in the Secretome of Irradiated Peripheral Blood Mononuclear Cells Supports In Vitro Osteoclastogenesis
por: Panahipour, Layla, et al.
Publicado: (2020)

Secretome of Stressed Peripheral Blood Mononuclear Cells Alters Transcriptome Signature in Heart, Liver, and Spleen after an Experimental Acute Myocardial Infarction: An In Silico Analysis
por: Mildner, Caterina Selina, et al.
Publicado: (2022)

Secretomes of apoptotic mononuclear cells ameliorate neurological damage in rats with focal ischemia
por: Altmann, Patrick, et al.
Publicado: (2014)

Peripheral blood mononuclear cell secretome for tissue repair
por: Beer, Lucian, et al.
Publicado: (2016)

Severity of thermal burn injury is associated with systemic neutrophil activation
por: Laggner, Maria, et al.
Publicado: (2022)

Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study
por: Lichtenauer, Michael, et al.
Publicado: (2011)

Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents – Implications for oxidative UV damage
por: Kremslehner, Christopher, et al.
Publicado: (2020)

Mechanical aortic valve prostheses offer a survival benefit in 50–65 year olds: AUTHEARTVISIT study
por: Traxler, Denise, et al.
Publicado: (2021)

Experimental Models for the Study of Hereditary Cornification Defects
por: Copic, Dragan, et al.
Publicado: (2021)

In vitro Stability of Heat Shock Protein 27 in Serum and Plasma Under Different Pre-analytical Conditions: Implications for Large-Scale Clinical Studies
por: Zimmermann, Matthias, et al.
Publicado: (2016)

Analysis of region specific gene expression patterns in the heart and systemic responses after experimental myocardial ischemia
por: Zimmermann, Matthias, et al.
Publicado: (2017)

Lipoprotein subfraction patterns throughout gestation in The Gambia: changes in subfraction composition and their relationships with infant birth weights
por: Woo, Jessica G., et al.
Publicado: (2023)

Mononuclear cell secretome protects from experimental autoimmune myocarditis
por: Hoetzenecker, Konrad, et al.
Publicado: (2015)

A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids
por: Narzt, Marie-Sophie, et al.
Publicado: (2018)

Role for Lipids Secreted by Irradiated Peripheral Blood Mononuclear Cells in Inflammatory Resolution in Vitro
por: Panahipour, Layla, et al.
Publicado: (2020)

Antithymocyte Globulin Inhibits CD8(+) T Cell Effector Functions via the Paracrine Induction of PDL-1 on Monocytes
por: Copic, Dragan, et al.
Publicado: (2023)

Clinical Relevance of Elevated Soluble ST2, HSP27 and 20S Proteasome at Hospital Admission in Patients with COVID-19
por: Wendt, Ralph, et al.
Publicado: (2021)

Sphingomyelinase Activity of Trichomonas vaginalis Extract and Subfractions
por: González-Salazar, Francisco, et al.
Publicado: (2013)

Histamine suppresses epidermal keratinocyte differentiation and impairs skin barrier function in a human skin model
por: Gschwandtner, M, et al.
Publicado: (2013)

Paracrine Factors of Stressed Peripheral Blood Mononuclear Cells Activate Proangiogenic and Anti-Proteolytic Processes in Whole Blood Cells and Protect the Endothelial Barrier
por: Copic, Dragan, et al.
Publicado: (2022)

Paracrine Factors from Irradiated Peripheral Blood Mononuclear Cells Improve Skin Regeneration and Angiogenesis in a Porcine Burn Model
por: Hacker, Stefan, et al.
Publicado: (2016)

Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands
por: Klas, Katharina, et al.
Publicado: (2021)

Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions
Publicado: (1992)

Hepatic Golgi fractions resolved into membrane and content subfractions
Publicado: (1982)

Nonalcoholic steatohepatitis is associated with an atherogenic lipoprotein subfraction profile
por: Corey, Kathleen E, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6l5v0fvvkanosbk7ujjuifq117