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Data on in vivo PGC-1alpha overexpression model via local transfection in aged mouse muscle
The data presented in this article are related to the research paper entitled “Intensified mitophagy in skeletal muscle with aging is downregulated by PGC-1alpha overexpression in vivo” (Yeo et al., 2019). The data explained the surgical procedure of in vivo local transfection by electroporation met...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301970/ https://www.ncbi.nlm.nih.gov/pubmed/30581926 http://dx.doi.org/10.1016/j.dib.2018.12.032 |
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author | Yeo, Dongwook Kang, Chounghun Gomez-Cabrera, Mari Carmen Vina, Jose Ji, Li Li |
author_facet | Yeo, Dongwook Kang, Chounghun Gomez-Cabrera, Mari Carmen Vina, Jose Ji, Li Li |
author_sort | Yeo, Dongwook |
collection | PubMed |
description | The data presented in this article are related to the research paper entitled “Intensified mitophagy in skeletal muscle with aging is downregulated by PGC-1alpha overexpression in vivo” (Yeo et al., 2019). The data explained the surgical procedure of in vivo local transfection by electroporation method in aged mouse tibialis anterior muscle, and plasmid DNA preparation and verification protocol. The data also showed the transfection efficiency levels of GFP or GFP-tagged PGC-1alpha through immunohistochemistry method for frozen muscle cross-sections. |
format | Online Article Text |
id | pubmed-6301970 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-63019702018-12-21 Data on in vivo PGC-1alpha overexpression model via local transfection in aged mouse muscle Yeo, Dongwook Kang, Chounghun Gomez-Cabrera, Mari Carmen Vina, Jose Ji, Li Li Data Brief Biochemistry, Genetics and Molecular Biology The data presented in this article are related to the research paper entitled “Intensified mitophagy in skeletal muscle with aging is downregulated by PGC-1alpha overexpression in vivo” (Yeo et al., 2019). The data explained the surgical procedure of in vivo local transfection by electroporation method in aged mouse tibialis anterior muscle, and plasmid DNA preparation and verification protocol. The data also showed the transfection efficiency levels of GFP or GFP-tagged PGC-1alpha through immunohistochemistry method for frozen muscle cross-sections. Elsevier 2018-12-13 /pmc/articles/PMC6301970/ /pubmed/30581926 http://dx.doi.org/10.1016/j.dib.2018.12.032 Text en © 2018 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Biochemistry, Genetics and Molecular Biology Yeo, Dongwook Kang, Chounghun Gomez-Cabrera, Mari Carmen Vina, Jose Ji, Li Li Data on in vivo PGC-1alpha overexpression model via local transfection in aged mouse muscle |
title | Data on in vivo PGC-1alpha overexpression model via local transfection in aged mouse muscle |
title_full | Data on in vivo PGC-1alpha overexpression model via local transfection in aged mouse muscle |
title_fullStr | Data on in vivo PGC-1alpha overexpression model via local transfection in aged mouse muscle |
title_full_unstemmed | Data on in vivo PGC-1alpha overexpression model via local transfection in aged mouse muscle |
title_short | Data on in vivo PGC-1alpha overexpression model via local transfection in aged mouse muscle |
title_sort | data on in vivo pgc-1alpha overexpression model via local transfection in aged mouse muscle |
topic | Biochemistry, Genetics and Molecular Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301970/ https://www.ncbi.nlm.nih.gov/pubmed/30581926 http://dx.doi.org/10.1016/j.dib.2018.12.032 |
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