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CRISPR/Cas9 Genome Editing to Disable the Latent HIV-1 Provirus

HIV-1 infection can be successfully controlled with anti-retroviral therapy (ART), but is not cured. A reservoir of cells harboring transcriptionally silent integrated provirus is able to reestablish replicating infection if ART is stopped. Latently HIV-1 infected cells are rare, but may persist for...

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Detalles Bibliográficos
Autores principales:	Panfil, Amanda R., London, James A., Green, Patrick L., Yoder, Kristine E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302043/ https://www.ncbi.nlm.nih.gov/pubmed/30619186 http://dx.doi.org/10.3389/fmicb.2018.03107

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