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Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs

The embryonic site of definitive hematopoietic stem cell (dHSC) origination has been debated for decades. Although an intra-embryonic origin is well supported, the yolk sac (YS) contribution to adult hematopoiesis remains controversial. The same developmental origin makes it difficult to identify sp...

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Detalles Bibliográficos
Autores principales:	Ganuza, Miguel, Chabot, Ashley, Tang, Xing, Bi, Wenjian, Natarajan, Sivaraman, Carter, Robert, Gawad, Charles, Kang, Guolian, Cheng, Yong, McKinney-Freeman, Shannon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302089/ https://www.ncbi.nlm.nih.gov/pubmed/30573729 http://dx.doi.org/10.1038/s41467-018-07769-8

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