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Ovarian Cancer-Intrinsic Fatty Acid Synthase Prevents Anti-tumor Immunity by Disrupting Tumor-Infiltrating Dendritic Cells

Fatty acid synthase (FASN), the key metabolic enzyme of de novo lipogenesis, provides proliferative and metastatic capacity directly to cancer cells have been described. However, the impact of aberrant activation of this lipogenic enzyme on host anti-tumor immune milieu remains unknown. In this stud...

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Detalles Bibliográficos
Autores principales:	Jiang, Li, Fang, Xuhong, Wang, Hong, Li, Diyou, Wang, Xipeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302125/ https://www.ncbi.nlm.nih.gov/pubmed/30619288 http://dx.doi.org/10.3389/fimmu.2018.02927

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