ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier

Podocytes, highly specialized epithelial cells, build the outer part of the kidney filtration barrier and withstand high mechanical forces through a complex network of cellular protrusions. Here, we show that Arp2/3-dependent actin polymerization controls actomyosin contractility and focal adhesion...

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Detalles Bibliográficos
Autores principales: Schell, Christoph, Sabass, Benedikt, Helmstaedter, Martin, Geist, Felix, Abed, Ahmed, Yasuda-Yamahara, Mako, Sigle, August, Maier, Jasmin I., Grahammer, Florian, Siegerist, Florian, Artelt, Nadine, Endlich, Nicole, Kerjaschki, Dontscho, Arnold, Hans-Henning, Dengjel, Jörn, Rogg, Manuel, Huber, Tobias B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302147/
https://www.ncbi.nlm.nih.gov/pubmed/30503751
http://dx.doi.org/10.1016/j.devcel.2018.11.011

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