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A case of autoimmune myositis after treatment with alemtuzumab for multiple sclerosis

Alemtuzumab is a high-efficacy disease-modifying therapy for the treatment of relapsing forms of multiple sclerosis and is associated with secondary autoimmune adverse events. We report a novel case of secondary autoimmune myositis that occurred seven months after the initial treatment cycle and ach...

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Detalles Bibliográficos
Autores principales: Aouad, Patrick, Yiannikas, Con, Fernando, Suran L, Parratt, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302273/
https://www.ncbi.nlm.nih.gov/pubmed/30622727
http://dx.doi.org/10.1177/2055217318819012
Descripción
Sumario:Alemtuzumab is a high-efficacy disease-modifying therapy for the treatment of relapsing forms of multiple sclerosis and is associated with secondary autoimmune adverse events. We report a novel case of secondary autoimmune myositis that occurred seven months after the initial treatment cycle and achieved full recovery with oral corticosteroids. This particular form of myositis appears to be unique, and is likely to be a distinct entity from the other four types of immune-mediated myositis.