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Demographics and Epidemiology of Osteochondritis Dissecans of the Elbow Among Children and Adolescents

BACKGROUND: Osteochondritis dissecans (OCD) of the elbow is a disorder of subchondral bone and articular cartilage, of which the incidence among children is not clearly known. PURPOSE: To assess the demographics and epidemiology of OCD of the elbow among children. STUDY DESIGN: Cross-sectional study...

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Autores principales: Kessler, Jeffrey I., Jacobs, John C., Cannamela, Peter C., Weiss, Jennifer M., Shea, Kevin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302285/
https://www.ncbi.nlm.nih.gov/pubmed/30622996
http://dx.doi.org/10.1177/2325967118815846
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author Kessler, Jeffrey I.
Jacobs, John C.
Cannamela, Peter C.
Weiss, Jennifer M.
Shea, Kevin G.
author_facet Kessler, Jeffrey I.
Jacobs, John C.
Cannamela, Peter C.
Weiss, Jennifer M.
Shea, Kevin G.
author_sort Kessler, Jeffrey I.
collection PubMed
description BACKGROUND: Osteochondritis dissecans (OCD) of the elbow is a disorder of subchondral bone and articular cartilage, of which the incidence among children is not clearly known. PURPOSE: To assess the demographics and epidemiology of OCD of the elbow among children. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: A retrospective chart review of an integrated health system for the years 2007 through 2011 was performed for patients with elbow OCD aged 2 to 19 years. Lesion location, laterality, and all patient demographics were recorded. OCD incidence was determined for the group as a whole as well as by sex and age group (2-5, 6-11, 12-19 years). Patient differences based on age, sex, and ethnicity were analyzed, and multivariable logistic regression models were used to assess the risk of elbow OCD by group. RESULTS: A total of 37 patients with 40 OCD lesions fit the inclusion criteria. No lesion was found among 2- to 5-year-olds. A majority of lesions (n = 39, 97.5%) were in the capitellum, and 1 (2.5%) was in the trochlea. Twenty-five patients (67.6%) had right-sided lesions; 9 (24.3%), left-sided; and 3 (8.1%), bilateral. The incidence of elbow OCD for patients aged 6 to 19 years was 2.2 per 100,000 overall and 3.8 and 0.6 per 100,000 for males and females, respectively. The majority of OCD cases were seen in those aged 12 to 19 years, with an incidence of 3.4 per 100,000 versus 0.38 among 6- to 11-year-olds. Multivariable logistic regression analysis revealed a 21.7-times increased odds ratio of elbow OCD among patients aged 12 to 19 years versus 6 to 11 years, and males had a 6.8-times greater odds ratio of elbow OCD than females (P < .0001 for both). Based on race and ethnicity, non-Hispanic whites had the highest incidence of elbow OCD as compared with all other ethnic groups. CONCLUSION: In this population-based cohort study of pediatric elbow OCD, males had almost 7 times the risk of elbow OCD as compared with females, and 12- to 19-year-olds had nearly 22 times the risk of elbow OCD versus 6- to 11-year-olds. In keeping with many prior studies, the majority of patients had right-sided lesions.
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spelling pubmed-63022852019-01-08 Demographics and Epidemiology of Osteochondritis Dissecans of the Elbow Among Children and Adolescents Kessler, Jeffrey I. Jacobs, John C. Cannamela, Peter C. Weiss, Jennifer M. Shea, Kevin G. Orthop J Sports Med Article BACKGROUND: Osteochondritis dissecans (OCD) of the elbow is a disorder of subchondral bone and articular cartilage, of which the incidence among children is not clearly known. PURPOSE: To assess the demographics and epidemiology of OCD of the elbow among children. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: A retrospective chart review of an integrated health system for the years 2007 through 2011 was performed for patients with elbow OCD aged 2 to 19 years. Lesion location, laterality, and all patient demographics were recorded. OCD incidence was determined for the group as a whole as well as by sex and age group (2-5, 6-11, 12-19 years). Patient differences based on age, sex, and ethnicity were analyzed, and multivariable logistic regression models were used to assess the risk of elbow OCD by group. RESULTS: A total of 37 patients with 40 OCD lesions fit the inclusion criteria. No lesion was found among 2- to 5-year-olds. A majority of lesions (n = 39, 97.5%) were in the capitellum, and 1 (2.5%) was in the trochlea. Twenty-five patients (67.6%) had right-sided lesions; 9 (24.3%), left-sided; and 3 (8.1%), bilateral. The incidence of elbow OCD for patients aged 6 to 19 years was 2.2 per 100,000 overall and 3.8 and 0.6 per 100,000 for males and females, respectively. The majority of OCD cases were seen in those aged 12 to 19 years, with an incidence of 3.4 per 100,000 versus 0.38 among 6- to 11-year-olds. Multivariable logistic regression analysis revealed a 21.7-times increased odds ratio of elbow OCD among patients aged 12 to 19 years versus 6 to 11 years, and males had a 6.8-times greater odds ratio of elbow OCD than females (P < .0001 for both). Based on race and ethnicity, non-Hispanic whites had the highest incidence of elbow OCD as compared with all other ethnic groups. CONCLUSION: In this population-based cohort study of pediatric elbow OCD, males had almost 7 times the risk of elbow OCD as compared with females, and 12- to 19-year-olds had nearly 22 times the risk of elbow OCD versus 6- to 11-year-olds. In keeping with many prior studies, the majority of patients had right-sided lesions. SAGE Publications 2018-12-19 /pmc/articles/PMC6302285/ /pubmed/30622996 http://dx.doi.org/10.1177/2325967118815846 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (http://www.creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Article
Kessler, Jeffrey I.
Jacobs, John C.
Cannamela, Peter C.
Weiss, Jennifer M.
Shea, Kevin G.
Demographics and Epidemiology of Osteochondritis Dissecans of the Elbow Among Children and Adolescents
title Demographics and Epidemiology of Osteochondritis Dissecans of the Elbow Among Children and Adolescents
title_full Demographics and Epidemiology of Osteochondritis Dissecans of the Elbow Among Children and Adolescents
title_fullStr Demographics and Epidemiology of Osteochondritis Dissecans of the Elbow Among Children and Adolescents
title_full_unstemmed Demographics and Epidemiology of Osteochondritis Dissecans of the Elbow Among Children and Adolescents
title_short Demographics and Epidemiology of Osteochondritis Dissecans of the Elbow Among Children and Adolescents
title_sort demographics and epidemiology of osteochondritis dissecans of the elbow among children and adolescents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302285/
https://www.ncbi.nlm.nih.gov/pubmed/30622996
http://dx.doi.org/10.1177/2325967118815846
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