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Oligomer Diversity during the Aggregation of the Repeat Region of Tau
[Image: see text] The molecular mechanism of protein aggregation is of both fundamental and clinical importance as amyloid aggregates are linked to a number of neurodegenerative disorders. Such protein aggregates include macroscopic insoluble fibrils as well as small soluble oligomeric species. Time...
Autores principales: | Kjaergaard, Magnus, Dear, Alexander J., Kundel, Franziska, Qamar, Seema, Meisl, Georg, Knowles, Tuomas P. J., Klenerman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302314/ https://www.ncbi.nlm.nih.gov/pubmed/29953200 http://dx.doi.org/10.1021/acschemneuro.8b00250 |
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