Emerging evidence linking the gut microbiome to neurologic disorders

The gut microbiome contributes to the development and function of the immune, metabolic, and nervous systems. Furthermore, commensal bacteria modulate symptoms and pathology in mouse models of neuropsychiatric and neurodevelopmental diseases. Uncovering mechanisms that are utilized by the microbiome...

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Detalles Bibliográficos
Autores principales: Griffiths, Jessica A., Mazmanian, Sarkis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302417/
https://www.ncbi.nlm.nih.gov/pubmed/30577867
http://dx.doi.org/10.1186/s13073-018-0609-3
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author Griffiths, Jessica A.
Mazmanian, Sarkis K.
author_facet Griffiths, Jessica A.
Mazmanian, Sarkis K.
author_sort Griffiths, Jessica A.
collection PubMed
description The gut microbiome contributes to the development and function of the immune, metabolic, and nervous systems. Furthermore, commensal bacteria modulate symptoms and pathology in mouse models of neuropsychiatric and neurodevelopmental diseases. Uncovering mechanisms that are utilized by the microbiome to mediate gut–brain connections may provide novel opportunities to target therapies to the gut in order to treat neurologic disorders.
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spelling pubmed-63024172018-12-31 Emerging evidence linking the gut microbiome to neurologic disorders Griffiths, Jessica A. Mazmanian, Sarkis K. Genome Med Comment The gut microbiome contributes to the development and function of the immune, metabolic, and nervous systems. Furthermore, commensal bacteria modulate symptoms and pathology in mouse models of neuropsychiatric and neurodevelopmental diseases. Uncovering mechanisms that are utilized by the microbiome to mediate gut–brain connections may provide novel opportunities to target therapies to the gut in order to treat neurologic disorders. BioMed Central 2018-12-21 /pmc/articles/PMC6302417/ /pubmed/30577867 http://dx.doi.org/10.1186/s13073-018-0609-3 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Griffiths, Jessica A.
Mazmanian, Sarkis K.
Emerging evidence linking the gut microbiome to neurologic disorders
title Emerging evidence linking the gut microbiome to neurologic disorders
title_full Emerging evidence linking the gut microbiome to neurologic disorders
title_fullStr Emerging evidence linking the gut microbiome to neurologic disorders
title_full_unstemmed Emerging evidence linking the gut microbiome to neurologic disorders
title_short Emerging evidence linking the gut microbiome to neurologic disorders
title_sort emerging evidence linking the gut microbiome to neurologic disorders
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302417/
https://www.ncbi.nlm.nih.gov/pubmed/30577867
http://dx.doi.org/10.1186/s13073-018-0609-3
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