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CCL1 is a major regulatory T cell attracting factor in human breast cancer

BACKGROUND: Regulatory T cells (Treg) suppress cytotoxic T cell anti-tumoral immune responses and thereby promote tumor progression. Prevention of intratumoral Treg accumulation by inhibition of their migration to the tumor microenvironment is a promising therapeutic strategy. The aim of this study...

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Detalles Bibliográficos
Autores principales: Kuehnemuth, Benjamin, Piseddu, Ignazio, Wiedemann, Gabriela M., Lauseker, Michael, Kuhn, Christina, Hofmann, Simone, Schmoeckel, Elisa, Endres, Stefan, Mayr, Doris, Jeschke, Udo, Anz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302432/
https://www.ncbi.nlm.nih.gov/pubmed/30572845
http://dx.doi.org/10.1186/s12885-018-5117-8