Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study

BACKGROUND: Although the genetic spectrum of human colorectal cancer (CRC) is mainly characterized by APC, KRAS and TP53 mutations, driver genes in tumor initiation have not been conclusively demonstrated. In this study, we aimed to identify novel markers for CRC. METHODS: We performed exome analysi...

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Detalles Bibliográficos
Autores principales: Chen, Erfei, Yang, Fangfang, He, Hongjuan, Li, Qiqi, Zhang, Wei, Xing, Jinliang, Zhu, Ziqing, Jiang, Jingjing, Wang, Hua, Zhao, Xiaojuan, Liu, Ruitao, Lei, Lei, Dong, Jing, Pei, Yuchen, Yang, Ying, Pan, Junqiang, Zhang, Pan, Liu, Shuzhen, Du, Le, Zeng, Yuan, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302470/
https://www.ncbi.nlm.nih.gov/pubmed/30572883
http://dx.doi.org/10.1186/s12943-018-0925-7

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