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Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis

BACKGROUND: Autophagy plays a crucial role in sustaining the homeostasis in various malignant diseases. It has also been reported to promote tumor development in multiple cancers. Glutaminolysis instead of Warburg Effect produce adequate ATP and provide nitrogen and carbon to replenish the TCA cycle...

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Detalles Bibliográficos
Autores principales: Zhang, Xing, Li, Zheng, Xuan, Zhe, Xu, Penghui, Wang, Weizhi, Chen, Zheng, Wang, Sen, Sun, Guangli, Xu, Jianghao, Xu, Zekuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302516/
https://www.ncbi.nlm.nih.gov/pubmed/30572959
http://dx.doi.org/10.1186/s13046-018-0993-y