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Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis
BACKGROUND: Autophagy plays a crucial role in sustaining the homeostasis in various malignant diseases. It has also been reported to promote tumor development in multiple cancers. Glutaminolysis instead of Warburg Effect produce adequate ATP and provide nitrogen and carbon to replenish the TCA cycle...
Autores principales: | Zhang, Xing, Li, Zheng, Xuan, Zhe, Xu, Penghui, Wang, Weizhi, Chen, Zheng, Wang, Sen, Sun, Guangli, Xu, Jianghao, Xu, Zekuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302516/ https://www.ncbi.nlm.nih.gov/pubmed/30572959 http://dx.doi.org/10.1186/s13046-018-0993-y |
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