Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii

Multilocus sequence typing has been useful for genotyping pathogens in surveillance and epidemiologic studies. However, it cannot reflect the true relationships of isolates for species with very dynamic genomes. Using a robust genome phylogeny, we demonstrated the limitations of this method for typi...

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Detalles Bibliográficos
Autores principales: Castillo-Ramírez, Santiago, Graña-Miraglia, Lucía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302598/
https://www.ncbi.nlm.nih.gov/pubmed/30561303
http://dx.doi.org/10.3201/eid2501.180374
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author Castillo-Ramírez, Santiago
Graña-Miraglia, Lucía
author_facet Castillo-Ramírez, Santiago
Graña-Miraglia, Lucía
author_sort Castillo-Ramírez, Santiago
collection PubMed
description Multilocus sequence typing has been useful for genotyping pathogens in surveillance and epidemiologic studies. However, it cannot reflect the true relationships of isolates for species with very dynamic genomes. Using a robust genome phylogeny, we demonstrated the limitations of this method for typing Acinetobacter baumannii.
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spelling pubmed-63025982019-01-01 Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii Castillo-Ramírez, Santiago Graña-Miraglia, Lucía Emerg Infect Dis Research Letter Multilocus sequence typing has been useful for genotyping pathogens in surveillance and epidemiologic studies. However, it cannot reflect the true relationships of isolates for species with very dynamic genomes. Using a robust genome phylogeny, we demonstrated the limitations of this method for typing Acinetobacter baumannii. Centers for Disease Control and Prevention 2019-01 /pmc/articles/PMC6302598/ /pubmed/30561303 http://dx.doi.org/10.3201/eid2501.180374 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Castillo-Ramírez, Santiago
Graña-Miraglia, Lucía
Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii
title Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii
title_full Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii
title_fullStr Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii
title_full_unstemmed Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii
title_short Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii
title_sort inaccurate multilocus sequence typing of acinetobacter baumannii
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302598/
https://www.ncbi.nlm.nih.gov/pubmed/30561303
http://dx.doi.org/10.3201/eid2501.180374
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