Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016

We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17% for 2007–2011, and 7.04% for 2012–2016. However, we ob...

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Detalles Bibliográficos
Autores principales: Buil, Jochem B., Snelders, Eveline, Denardi, Laura Bedin, Melchers, Willem J.G., Verweij, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302600/
https://www.ncbi.nlm.nih.gov/pubmed/30561296
http://dx.doi.org/10.3201/eid2501.171925
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author Buil, Jochem B.
Snelders, Eveline
Denardi, Laura Bedin
Melchers, Willem J.G.
Verweij, Paul E.
author_facet Buil, Jochem B.
Snelders, Eveline
Denardi, Laura Bedin
Melchers, Willem J.G.
Verweij, Paul E.
author_sort Buil, Jochem B.
collection PubMed
description We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17% for 2007–2011, and 7.04% for 2012–2016. However, we observed substantial variation between years.
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spelling pubmed-63026002019-01-01 Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016 Buil, Jochem B. Snelders, Eveline Denardi, Laura Bedin Melchers, Willem J.G. Verweij, Paul E. Emerg Infect Dis Research Letter We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17% for 2007–2011, and 7.04% for 2012–2016. However, we observed substantial variation between years. Centers for Disease Control and Prevention 2019-01 /pmc/articles/PMC6302600/ /pubmed/30561296 http://dx.doi.org/10.3201/eid2501.171925 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Buil, Jochem B.
Snelders, Eveline
Denardi, Laura Bedin
Melchers, Willem J.G.
Verweij, Paul E.
Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016
title Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016
title_full Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016
title_fullStr Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016
title_full_unstemmed Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016
title_short Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016
title_sort trends in azole resistance in aspergillus fumigatus, the netherlands, 1994–2016
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302600/
https://www.ncbi.nlm.nih.gov/pubmed/30561296
http://dx.doi.org/10.3201/eid2501.171925
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