Cargando…
Comparison of serum procalcitonin level with erythrocytes sedimentation rate, C-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in Motahhari hospital of Urmia (2016)
Blood infection is one of the causes of morbidity in hospitalized patients. While some scholars have identified procalcitonin (PCT) as a potential biomarker for the diagnosis of blood infection, others have questioned its diagnostic value. Thus, the present study was conducted to compare the diagnos...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302684/ https://www.ncbi.nlm.nih.gov/pubmed/30637233 http://dx.doi.org/10.4103/japtr.JAPTR_319_18 |
_version_ | 1783382032720592896 |
---|---|
author | Nasimfar, Amir Sadeghi, Ebrahim Karamyyar, Mohammad Manesh, Laya Javan |
author_facet | Nasimfar, Amir Sadeghi, Ebrahim Karamyyar, Mohammad Manesh, Laya Javan |
author_sort | Nasimfar, Amir |
collection | PubMed |
description | Blood infection is one of the causes of morbidity in hospitalized patients. While some scholars have identified procalcitonin (PCT) as a potential biomarker for the diagnosis of blood infection, others have questioned its diagnostic value. Thus, the present study was conducted to compare the diagnostic values of PCT with C-reactive protein (CRP), erythrocytes sedimentation rate (ESR), white blood cell (WBC) count, and blood culture in patients with bacterial blood infections. In a prospective case–control study, 45 septic patients (6 months–5 years old), who were hospitalized in Shahid Motahhari Hospital of Urmia over the year 2016 and 45 patients with noninfectious diseases, whose gender and age range were similar to the members of the septic group, were examined. The participants’ blood samples were taken for the sake of blood culture and measurement of PCT level, ESR, and CRP. Finally, the collected data were analyzed through the SPSS-21 software. the results indicated that the average PCT, ESR, CRP, and WBC count was significantly higher in septic patients. Moreover, the blood culture of patients with negative or intermediate serum PCT levels was negative, while 50% of blood culture results in patients with positive PCT were positive and the rest were negative. Finally, a significant relationship was detected between the frequency of blood culture results and results of serum PCT tests (P = 0.003). serum PCT level can be considered a diagnostic marker of bacterial infections. If used in conjunction with tests of CRP, ESR, and WBC count, the PCT test can enhance the diagnosis of bacterial infections. |
format | Online Article Text |
id | pubmed-6302684 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-63026842019-01-11 Comparison of serum procalcitonin level with erythrocytes sedimentation rate, C-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in Motahhari hospital of Urmia (2016) Nasimfar, Amir Sadeghi, Ebrahim Karamyyar, Mohammad Manesh, Laya Javan J Adv Pharm Technol Res Original Article Blood infection is one of the causes of morbidity in hospitalized patients. While some scholars have identified procalcitonin (PCT) as a potential biomarker for the diagnosis of blood infection, others have questioned its diagnostic value. Thus, the present study was conducted to compare the diagnostic values of PCT with C-reactive protein (CRP), erythrocytes sedimentation rate (ESR), white blood cell (WBC) count, and blood culture in patients with bacterial blood infections. In a prospective case–control study, 45 septic patients (6 months–5 years old), who were hospitalized in Shahid Motahhari Hospital of Urmia over the year 2016 and 45 patients with noninfectious diseases, whose gender and age range were similar to the members of the septic group, were examined. The participants’ blood samples were taken for the sake of blood culture and measurement of PCT level, ESR, and CRP. Finally, the collected data were analyzed through the SPSS-21 software. the results indicated that the average PCT, ESR, CRP, and WBC count was significantly higher in septic patients. Moreover, the blood culture of patients with negative or intermediate serum PCT levels was negative, while 50% of blood culture results in patients with positive PCT were positive and the rest were negative. Finally, a significant relationship was detected between the frequency of blood culture results and results of serum PCT tests (P = 0.003). serum PCT level can be considered a diagnostic marker of bacterial infections. If used in conjunction with tests of CRP, ESR, and WBC count, the PCT test can enhance the diagnosis of bacterial infections. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6302684/ /pubmed/30637233 http://dx.doi.org/10.4103/japtr.JAPTR_319_18 Text en Copyright: © 2018 Journal of Advanced Pharmaceutical Technology & Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Nasimfar, Amir Sadeghi, Ebrahim Karamyyar, Mohammad Manesh, Laya Javan Comparison of serum procalcitonin level with erythrocytes sedimentation rate, C-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in Motahhari hospital of Urmia (2016) |
title | Comparison of serum procalcitonin level with erythrocytes sedimentation rate, C-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in Motahhari hospital of Urmia (2016) |
title_full | Comparison of serum procalcitonin level with erythrocytes sedimentation rate, C-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in Motahhari hospital of Urmia (2016) |
title_fullStr | Comparison of serum procalcitonin level with erythrocytes sedimentation rate, C-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in Motahhari hospital of Urmia (2016) |
title_full_unstemmed | Comparison of serum procalcitonin level with erythrocytes sedimentation rate, C-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in Motahhari hospital of Urmia (2016) |
title_short | Comparison of serum procalcitonin level with erythrocytes sedimentation rate, C-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in Motahhari hospital of Urmia (2016) |
title_sort | comparison of serum procalcitonin level with erythrocytes sedimentation rate, c-reactive protein, white blood cell count, and blood culture in the diagnosis of bacterial infections in patients hospitalized in motahhari hospital of urmia (2016) |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302684/ https://www.ncbi.nlm.nih.gov/pubmed/30637233 http://dx.doi.org/10.4103/japtr.JAPTR_319_18 |
work_keys_str_mv | AT nasimfaramir comparisonofserumprocalcitoninlevelwitherythrocytessedimentationratecreactiveproteinwhitebloodcellcountandbloodcultureinthediagnosisofbacterialinfectionsinpatientshospitalizedinmotahharihospitalofurmia2016 AT sadeghiebrahim comparisonofserumprocalcitoninlevelwitherythrocytessedimentationratecreactiveproteinwhitebloodcellcountandbloodcultureinthediagnosisofbacterialinfectionsinpatientshospitalizedinmotahharihospitalofurmia2016 AT karamyyarmohammad comparisonofserumprocalcitoninlevelwitherythrocytessedimentationratecreactiveproteinwhitebloodcellcountandbloodcultureinthediagnosisofbacterialinfectionsinpatientshospitalizedinmotahharihospitalofurmia2016 AT maneshlayajavan comparisonofserumprocalcitoninlevelwitherythrocytessedimentationratecreactiveproteinwhitebloodcellcountandbloodcultureinthediagnosisofbacterialinfectionsinpatientshospitalizedinmotahharihospitalofurmia2016 |