Cargando…

Using Chromatin Architecture to Understand the Genetics and Transcriptomics of Juvenile Idiopathic Arthritis

The presence of abnormal gene expression signatures is a well-described feature of the oligoarticular and polyarticular forms of juvenile idiopathic arthritis. In this review, we discuss how new insights into genetic risk for JIA and the three dimensional architecture of the genome may be used to de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kessler, Haeja, Jiang, Kaiyu, Jarvis, James N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302745/ https://www.ncbi.nlm.nih.gov/pubmed/30619322 http://dx.doi.org/10.3389/fimmu.2018.02964

Ejemplares similares

Broadening our understanding of the genetics of Juvenile Idiopathic Arthritis (JIA): Interrogation of three dimensional chromatin structures and genetic regulatory elements within JIA-associated risk loci
por: Jiang, Kaiyu, et al.
Publicado: (2020)

Chromatin landscapes and genetic risk for juvenile idiopathic arthritis
por: Zhu, Lisha, et al.
Publicado: (2017)

Analysis of chromatin data supports a role for CD14+ monocytes/macrophages in mediating genetic risk for juvenile idiopathic arthritis
por: Crinzi, Elizabeth A., et al.
Publicado: (2022)

Complexity and Specificity of the Neutrophil Transcriptomes in Juvenile Idiopathic Arthritis
por: Hu, Zihua, et al.
Publicado: (2016)

Genetic insights into juvenile idiopathic arthritis derived from deep whole genome sequencing
por: Wong, Laiping, et al.
Publicado: (2017)

Genomic characterization of remission in juvenile idiopathic arthritis
por: Jiang, Kaiyu, et al.
Publicado: (2013)

Genetic architecture study of rheumatoid arthritis and juvenile idiopathic arthritis
por: Jia, Jun, et al.
Publicado: (2020)

Modeling Transcriptional Rewiring in Neutrophils Through the Course of Treated Juvenile Idiopathic Arthritis
por: Hu, Zihua, et al.
Publicado: (2018)

CD4+ T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities
por: Tarbell, Evan, et al.
Publicado: (2021)

Dynamic tracking of functional gene modules in treated juvenile idiopathic arthritis
por: Du, Nan, et al.
Publicado: (2015)

Immune Complexes in Juvenile Idiopathic Arthritis
por: Moore, Terry L.
Publicado: (2016)

Limits of Peripheral Blood Mononuclear Cells for Gene Expression-Based Biomarkers in Juvenile Idiopathic Arthritis
por: Wong, Laiping, et al.
Publicado: (2016)

Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications
por: Ombrello, Michael J, et al.
Publicado: (2017)

The Multi-Omics Architecture of Juvenile Idiopathic Arthritis
por: Hou, Xiaoyuan, et al.
Publicado: (2020)

Autoantibodies in the Pathogenesis, Diagnosis, and Prognosis of Juvenile Idiopathic Arthritis
por: Mahmud, Shawn A., et al.
Publicado: (2019)

Targeting Tregs in Juvenile Idiopathic Arthritis and Juvenile Dermatomyositis—Insights From Other Diseases
por: Hoeppli, Romy E., et al.
Publicado: (2019)

Whole blood expression profiling from the TREAT trial: insights for the pathogenesis of polyarticular juvenile idiopathic arthritis
por: Jiang, Kaiyu, et al.
Publicado: (2016)

Foxp3 Molecular Dynamics in Treg in Juvenile Idiopathic Arthritis
por: Copland, Alastair, et al.
Publicado: (2018)

Expanded population of low-density neutrophils in juvenile idiopathic arthritis
por: Parackova, Zuzana, et al.
Publicado: (2023)

Whole Blood Gene Expression Profiling Predicts Therapeutic Response at Six Months in Patients With Polyarticular Juvenile Idiopathic Arthritis
por: Jiang, Kaiyu, et al.
Publicado: (2014)

Whole Transcriptome Analysis Reveals Heterogeneity in B Cell Memory Populations in Patients With Juvenile Idiopathic Arthritis-Associated Uveitis
por: Wennink, Roos A. W., et al.
Publicado: (2020)

Th17 and Th1 Lymphocytes in Oligoarticular Juvenile Idiopathic Arthritis
por: Maggi, Laura, et al.
Publicado: (2019)

Identification of Ocular Autoantigens Associated With Juvenile Idiopathic Arthritis-Associated Uveitis
por: Busch, Martin, et al.
Publicado: (2019)

Neutrophil Homeostasis and Emergency Granulopoiesis: The Example of Systemic Juvenile Idiopathic Arthritis
por: Malengier-Devlies, Bert, et al.
Publicado: (2021)

A Cross-Tissue Transcriptome-Wide Association Study Identifies Novel Susceptibility Genes for Juvenile Idiopathic Arthritis in Asia and Europe
por: Xu, Jiawen, et al.
Publicado: (2022)

Lung Functioning and Inflammation in a Mouse Model of Systemic Juvenile Idiopathic Arthritis
por: Malengier-Devlies, Bert, et al.
Publicado: (2021)

Study of the shared gene signatures of polyarticular juvenile idiopathic arthritis and autoimmune uveitis
por: Zheng, Jie, et al.
Publicado: (2023)

The feasibility of developing biomarkers from peripheral blood mononuclear cell RNAseq data in children with juvenile idiopathic arthritis using machine learning approaches
por: Poppenberg, Kerry E., et al.
Publicado: (2019)

Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes
por: Poppenberg, Kerry E., et al.
Publicado: (2021)

A comprehensive review of the genetics of juvenile idiopathic arthritis
por: Prahalad, Sampath, et al.
Publicado: (2008)

Safety and Effectiveness of Tofacitinib in Treating Polyarticular Course Juvenile Idiopathic Arthritis
por: Jones, Nicholas T, et al.
Publicado: (2023)

Restoring T Cell Tolerance, Exploring the Potential of Histone Deacetylase Inhibitors for the Treatment of Juvenile Idiopathic Arthritis
por: Nijhuis, Lotte, et al.
Publicado: (2019)

Impact of Kawasaki disease on juvenile idiopathic arthritis in real-world patients: A population-based cohort study
por: Liao, Li-Chin, et al.
Publicado: (2022)

Juvenile idiopathic arthritis
por: Bhatt, Krupa H, et al.
Publicado: (2014)

Juvenile Idiopathic Arthritis
por: Barut, Kenan, et al.
Publicado: (2017)

Is juvenile rheumatoid arthritis/juvenile idiopathic arthritis different from rheumatoid arthritis?
por: Prahalad, Sampath, et al.
Publicado: (2002)

Novel approaches to gene expression analysis of active polyarticular juvenile rheumatoid arthritis
por: Jarvis, James N, et al.
Publicado: (2004)

Chromatin landscapes and genetic risk in systemic lupus
por: Hui-Yuen, Joyce S., et al.
Publicado: (2016)

Differential Accumulation and Activation of Monocyte and Dendritic Cell Subsets in Inflamed Synovial Fluid Discriminates Between Juvenile Idiopathic Arthritis and Septic Arthritis
por: Cren, Maïlys, et al.
Publicado: (2020)

Genetic markers in clinical subtypes of juvenile idiopathic arthritis
por: Le Blay, Pierre, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_dog711lotp9ejh6l5uu1esoa6l