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Neuroprotective effect of insulin-loaded chitosan nanoparticles/PLGA-PEG-PLGA hydrogel on diabetic retinopathy in rats

BACKGROUND: To pursuit effective sustained release systems for insulin to treat diabetic retinopathy (DR), a novel insulin delivering system was developed via loading onto chitosan nanoparticles/poly(lactic-co-glycolic acid)-poly(ethylene glycol)-poly(lactic-co-glycolic acid) hydrogel (ICNPH). METHO...

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Detalles Bibliográficos
Autores principales:	Rong, Xianfang, Ji, Yinghong, Zhu, Xiangjia, Yang, Jin, Qian, Dongjin, Mo, Xiaofen, Lu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302824/ https://www.ncbi.nlm.nih.gov/pubmed/30587984 http://dx.doi.org/10.2147/IJN.S184574

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