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A multi-sequence and habitat-based MRI radiomics signature for preoperative prediction of MGMT promoter methylation in astrocytomas with prognostic implication

OBJECTIVES: Oxygen 6-methylguanine-DNA methyltransferase (MGMT) promoter methylation is a significant prognostic biomarker in astrocytomas, especially for temozolomide (TMZ) chemotherapy. This study aimed to preoperatively predict MGMT methylation status based on magnetic resonance imaging (MRI) rad...

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Detalles Bibliográficos
Autores principales:	Wei, Jingwei, Yang, Guoqiang, Hao, Xiaohan, Gu, Dongsheng, Tan, Yan, Wang, Xiaochun, Dong, Di, Zhang, Shuaitong, Wang, Le, Zhang, Hui, Tian, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Computer Applications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302873/ https://www.ncbi.nlm.nih.gov/pubmed/30039219 http://dx.doi.org/10.1007/s00330-018-5575-z

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