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A repressor-decay timer for robust temporal patterning in embryonic Drosophila neuroblast lineages

Biological timers synchronize patterning processes during embryonic development. In the Drosophila embryo, neural progenitors (neuroblasts; NBs) produce a sequence of unique neurons whose identities depend on the sequential expression of temporal transcription factors (TTFs). The stereotypy and prec...

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Detalles Bibliográficos
Autores principales: Averbukh, Inna, Lai, Sen-Lin, Doe, Chris Q, Barkai, Naama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303102/
https://www.ncbi.nlm.nih.gov/pubmed/30526852
http://dx.doi.org/10.7554/eLife.38631