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Forensic STR profiling based smart barcode, a highly efficient and cost effective human identification system

In forensic science, the human identification is the major goal in criminal cases and in paternity dispute, based on DNA profiling of individual. Analysis of short tandem repeat (STRs) markers used as a reliable technique for this purpose. In this study the main objective was to develop a human iden...

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Detalles Bibliográficos
Autores principales: Zahra, Andleeb, Hussain, Bilal, Jamil, Amer, Ahmed, Z., Mahboob, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303164/
https://www.ncbi.nlm.nih.gov/pubmed/30591790
http://dx.doi.org/10.1016/j.sjbs.2018.10.001
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author Zahra, Andleeb
Hussain, Bilal
Jamil, Amer
Ahmed, Z.
Mahboob, Shahid
author_facet Zahra, Andleeb
Hussain, Bilal
Jamil, Amer
Ahmed, Z.
Mahboob, Shahid
author_sort Zahra, Andleeb
collection PubMed
description In forensic science, the human identification is the major goal in criminal cases and in paternity dispute, based on DNA profiling of individual. Analysis of short tandem repeat (STRs) markers used as a reliable technique for this purpose. In this study the main objective was to develop a human identification based on DNA fingerprinting using Human Identification Barcode System (HIBS). HIBS may be used to provide a unique molecular signature of human in the form of a barcode. DNA was isolated from blood by using PCR technique to detect bands to design human barcode using self-designed system. HIBS is a web based application that can be accessed via www.hibs.com.pk. HIBS can be accessed with internet access and may be introduced on security checkpoints to identify an individual based on his own DNA instead of conventional procedures of identification. The barcode generated through DNA fingerprinting will be stored in a HIBS, and may also be a part of CNIC. It may be successfully used against suicide bombers, target killers, etc., as even a single blood spot, a few skin cells, root of the hair etc., to identify such culprits. It may also be effectively used to relieve the individuals with false accusations.
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spelling pubmed-63031642018-12-27 Forensic STR profiling based smart barcode, a highly efficient and cost effective human identification system Zahra, Andleeb Hussain, Bilal Jamil, Amer Ahmed, Z. Mahboob, Shahid Saudi J Biol Sci Article In forensic science, the human identification is the major goal in criminal cases and in paternity dispute, based on DNA profiling of individual. Analysis of short tandem repeat (STRs) markers used as a reliable technique for this purpose. In this study the main objective was to develop a human identification based on DNA fingerprinting using Human Identification Barcode System (HIBS). HIBS may be used to provide a unique molecular signature of human in the form of a barcode. DNA was isolated from blood by using PCR technique to detect bands to design human barcode using self-designed system. HIBS is a web based application that can be accessed via www.hibs.com.pk. HIBS can be accessed with internet access and may be introduced on security checkpoints to identify an individual based on his own DNA instead of conventional procedures of identification. The barcode generated through DNA fingerprinting will be stored in a HIBS, and may also be a part of CNIC. It may be successfully used against suicide bombers, target killers, etc., as even a single blood spot, a few skin cells, root of the hair etc., to identify such culprits. It may also be effectively used to relieve the individuals with false accusations. Elsevier 2018-12 2018-10-02 /pmc/articles/PMC6303164/ /pubmed/30591790 http://dx.doi.org/10.1016/j.sjbs.2018.10.001 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Zahra, Andleeb
Hussain, Bilal
Jamil, Amer
Ahmed, Z.
Mahboob, Shahid
Forensic STR profiling based smart barcode, a highly efficient and cost effective human identification system
title Forensic STR profiling based smart barcode, a highly efficient and cost effective human identification system
title_full Forensic STR profiling based smart barcode, a highly efficient and cost effective human identification system
title_fullStr Forensic STR profiling based smart barcode, a highly efficient and cost effective human identification system
title_full_unstemmed Forensic STR profiling based smart barcode, a highly efficient and cost effective human identification system
title_short Forensic STR profiling based smart barcode, a highly efficient and cost effective human identification system
title_sort forensic str profiling based smart barcode, a highly efficient and cost effective human identification system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303164/
https://www.ncbi.nlm.nih.gov/pubmed/30591790
http://dx.doi.org/10.1016/j.sjbs.2018.10.001
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