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Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients

OBJECTIVE: To study the effect on pain of per-cutaneous cementoplasty for painful extraspinal bone metastasis. METHOD: 43 patients with extraspinal bone metastasis were included between April 2006 and October 2014 in this retrospective monocenter study. The primary endpoint was pain level measured o...

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Autores principales: Couraud, Gaëlle, André-Pierre, Gaston, Titien, Tulier, Florent, Eymard, Alexia, Hourdille, Xavier-Jean, Chevalier, Boussion, Hélene, Sandra, Guignard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303380/
https://www.ncbi.nlm.nih.gov/pubmed/30591867
http://dx.doi.org/10.1016/j.jbo.2018.09.004
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author Couraud, Gaëlle
André-Pierre, Gaston
Titien, Tulier
Florent, Eymard
Alexia, Hourdille
Xavier-Jean, Chevalier
Boussion, Hélene
Sandra, Guignard
author_facet Couraud, Gaëlle
André-Pierre, Gaston
Titien, Tulier
Florent, Eymard
Alexia, Hourdille
Xavier-Jean, Chevalier
Boussion, Hélene
Sandra, Guignard
author_sort Couraud, Gaëlle
collection PubMed
description OBJECTIVE: To study the effect on pain of per-cutaneous cementoplasty for painful extraspinal bone metastasis. METHOD: 43 patients with extraspinal bone metastasis were included between April 2006 and October 2014 in this retrospective monocenter study. The primary endpoint was pain level measured on a 0–10 numeric rating scale at week 1 after cementoplasty as compared with pre-cementoplasty. Secondary endpoints were long-term pain level and impact on quality of life and disability. RESULTS: Mean pain score was 4.2 (SD ±3.6) before cementoplasty and 1.09 (SD ±2.4) at week 1 (p = 0.005) (n = 31 patients). At 22 months after cementoplasty, quality of life and disability improved (according to the patient global assessment) for 47.6% and 52.2% of patients (n = 21patients). We did not find a predictor of good response. Cement leakage was the most common adverse event. CONCLUSION: Percutaneous cementoplasty of extraspinal bone metastasis is a rapidly efficient treatment with few adverse events. Its efficacy persists over time, with a benefit for disability and quality of life. Although this technique is only palliative, it should be considered in this situation.
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spelling pubmed-63033802018-12-27 Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients Couraud, Gaëlle André-Pierre, Gaston Titien, Tulier Florent, Eymard Alexia, Hourdille Xavier-Jean, Chevalier Boussion, Hélene Sandra, Guignard J Bone Oncol Research Article OBJECTIVE: To study the effect on pain of per-cutaneous cementoplasty for painful extraspinal bone metastasis. METHOD: 43 patients with extraspinal bone metastasis were included between April 2006 and October 2014 in this retrospective monocenter study. The primary endpoint was pain level measured on a 0–10 numeric rating scale at week 1 after cementoplasty as compared with pre-cementoplasty. Secondary endpoints were long-term pain level and impact on quality of life and disability. RESULTS: Mean pain score was 4.2 (SD ±3.6) before cementoplasty and 1.09 (SD ±2.4) at week 1 (p = 0.005) (n = 31 patients). At 22 months after cementoplasty, quality of life and disability improved (according to the patient global assessment) for 47.6% and 52.2% of patients (n = 21patients). We did not find a predictor of good response. Cement leakage was the most common adverse event. CONCLUSION: Percutaneous cementoplasty of extraspinal bone metastasis is a rapidly efficient treatment with few adverse events. Its efficacy persists over time, with a benefit for disability and quality of life. Although this technique is only palliative, it should be considered in this situation. Elsevier 2018-09-19 /pmc/articles/PMC6303380/ /pubmed/30591867 http://dx.doi.org/10.1016/j.jbo.2018.09.004 Text en © 2018 Hopital Henri Mondor - Service Rhumatologie. Published by Elsevier GmbH. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Couraud, Gaëlle
André-Pierre, Gaston
Titien, Tulier
Florent, Eymard
Alexia, Hourdille
Xavier-Jean, Chevalier
Boussion, Hélene
Sandra, Guignard
Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients
title Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients
title_full Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients
title_fullStr Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients
title_full_unstemmed Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients
title_short Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients
title_sort evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: a monocenter study of 31 patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303380/
https://www.ncbi.nlm.nih.gov/pubmed/30591867
http://dx.doi.org/10.1016/j.jbo.2018.09.004
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