The interactions of novel mononuclear platinum-based complexes with DNA

BACKGROUND: Cisplatin has been widely used for the treatment of cancer and its antitumour activity is attributed to its capacity to form DNA adducts, predominantly at guanine residues, which impede cellular processes such as DNA replication and transcription. However, there are associated toxicity a...

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Detalles Bibliográficos
Autores principales: Johnson, Ben W., Burgess, Mark W., Murray, Vincent, Aldrich-Wright, Janice R., Temple, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303901/
https://www.ncbi.nlm.nih.gov/pubmed/30577821
http://dx.doi.org/10.1186/s12885-018-5194-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303901/
https://www.ncbi.nlm.nih.gov/pubmed/30577821
http://dx.doi.org/10.1186/s12885-018-5194-8

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