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Ras-ERK1/2 signaling contributes to the development of colorectal cancer via regulating H3K9ac

BACKGROUNDS/AIMS: Ras is a control switch of ERK1/2 pathway, and hyperactivation of Ras-ERK1/2 signaling appears frequently in human cancers. However, the molecular regulation following by Ras-ERK1/2 activation is still unclear. This work aimed to reveal whether Ras-ERK1/2 promoted the development o...

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Detalles Bibliográficos
Autores principales: Tian, Peng, Zhu, Yanfei, Zhang, Chao, Guo, Xinyu, Zhang, Peng, Xue, Huanzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303919/
https://www.ncbi.nlm.nih.gov/pubmed/30577849
http://dx.doi.org/10.1186/s12885-018-5199-3