GJA1 (connexin43) is a key regulator of Alzheimer’s disease pathogenesis

GJA1 (connexin43) has been predicted as the top key driver of an astrocyte enriched subnetwork associated with Alzheimer’s disease (AD). In this study, we comprehensively examined GJA1 expression across 29 transcriptomic and proteomic datasets from post-mortem AD and normal control brains. We demons...

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Detalles Bibliográficos
Autores principales: Kajiwara, Yuji, Wang, Erming, Wang, Minghui, Sin, Wun Chey, Brennand, Kristen J., Schadt, Eric, Naus, Christian C., Buxbaum, Joseph, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303945/
https://www.ncbi.nlm.nih.gov/pubmed/30577786
http://dx.doi.org/10.1186/s40478-018-0642-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303945/
https://www.ncbi.nlm.nih.gov/pubmed/30577786
http://dx.doi.org/10.1186/s40478-018-0642-x

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