Cargando…
GJA1 (connexin43) is a key regulator of Alzheimer’s disease pathogenesis
GJA1 (connexin43) has been predicted as the top key driver of an astrocyte enriched subnetwork associated with Alzheimer’s disease (AD). In this study, we comprehensively examined GJA1 expression across 29 transcriptomic and proteomic datasets from post-mortem AD and normal control brains. We demons...
Autores principales: | Kajiwara, Yuji, Wang, Erming, Wang, Minghui, Sin, Wun Chey, Brennand, Kristen J., Schadt, Eric, Naus, Christian C., Buxbaum, Joseph, Zhang, Bin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303945/ https://www.ncbi.nlm.nih.gov/pubmed/30577786 http://dx.doi.org/10.1186/s40478-018-0642-x |
Ejemplares similares
-
Role of Gap Junction Protein Connexin43 in Astrogliosis Induced by Brain Injury
por: Theodoric, Nicolas, et al.
Publicado: (2012) -
Conflicting Roles of Connexin43 in Tumor Invasion and Growth in the Central Nervous System
por: Uzu, Miaki, et al.
Publicado: (2018) -
Internal translation of Gja1 (Connexin43) to produce GJA1-20k: Implications for arrhythmia and ischemic-preconditioning
por: Whisenant, Claire C., et al.
Publicado: (2022) -
The Complex Subtype-Dependent Role of Connexin 43 (GJA1) in Breast Cancer
por: Busby, Mélanie, et al.
Publicado: (2018) -
Cx43 in Neural Progenitors Promotes Glioma Invasion in a 3D Culture System
por: Khosla, Kanika, et al.
Publicado: (2020)