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Speckle-type POZ protein functions as a tumor suppressor in non-small cell lung cancer due to DNA methylation

BACKGROUND: Tumor suppressor epigenetic silencing plays an important role in non-small cell lung cancer (NSCLC) development and progression. Previously, the expression of speckle-type POZ protein (SPOP) has been found to be significantly inhibited in NSCLC. Our research aimed to investigate the mole...

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Detalles Bibliográficos
Autores principales:	Yao, Sumei, Chen, Xinming, Chen, Jinliang, Guan, Yangbo, Liu, Yifei, Chen, Jianrong, Lv, Xuedong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304003/ https://www.ncbi.nlm.nih.gov/pubmed/30607139 http://dx.doi.org/10.1186/s12935-018-0711-z

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