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Chronic cadmium exposure aggravates malignant phenotypes of nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway via hypermethylation of the casein kinase 1α promoter

BACKGROUND: Our previous study has shown that cadmium (Cd) exposure is not only a risk factor for nasopharyngeal carcinoma (NPC), but also correlated with the clinical stage and lymph node metastasis. However, the underlying molecular events of Cd involved in NPC progression remain to be elucidated....

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Detalles Bibliográficos
Autores principales: Peng, Lin, Huang, Yi-Teng, Zhang, Fan, Chen, Jiong-Yu, Huo, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304082/
https://www.ncbi.nlm.nih.gov/pubmed/30588112
http://dx.doi.org/10.2147/CMAR.S171200