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Chronic cadmium exposure aggravates malignant phenotypes of nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway via hypermethylation of the casein kinase 1α promoter
BACKGROUND: Our previous study has shown that cadmium (Cd) exposure is not only a risk factor for nasopharyngeal carcinoma (NPC), but also correlated with the clinical stage and lymph node metastasis. However, the underlying molecular events of Cd involved in NPC progression remain to be elucidated....
Autores principales: | Peng, Lin, Huang, Yi-Teng, Zhang, Fan, Chen, Jiong-Yu, Huo, Xia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304082/ https://www.ncbi.nlm.nih.gov/pubmed/30588112 http://dx.doi.org/10.2147/CMAR.S171200 |
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