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Sclerosing angiomatoid nodular transformation of the spleen (SANT) in a patient with clear cell carcinoma of the uterus: a case report

BACKGROUND: Sclerosing angiomatoid nodular transformation of the spleen is a very rare benign vascular lesion recently described. Usually, sclerosing angiomatoid nodular transformation of the spleen is an incidental finding; the association with malignant tumors is extremely rare. To the best of our...

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Autores principales: Efared, Boubacar, Sidibé, Ibrahim S., Erregad, Fatimazahra, Hammas, Nawal, Chbani, Laila, El Fatemi, Hinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304231/
https://www.ncbi.nlm.nih.gov/pubmed/30579362
http://dx.doi.org/10.1186/s13256-018-1907-5
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author Efared, Boubacar
Sidibé, Ibrahim S.
Erregad, Fatimazahra
Hammas, Nawal
Chbani, Laila
El Fatemi, Hinde
author_facet Efared, Boubacar
Sidibé, Ibrahim S.
Erregad, Fatimazahra
Hammas, Nawal
Chbani, Laila
El Fatemi, Hinde
author_sort Efared, Boubacar
collection PubMed
description BACKGROUND: Sclerosing angiomatoid nodular transformation of the spleen is a very rare benign vascular lesion recently described. Usually, sclerosing angiomatoid nodular transformation of the spleen is an incidental finding; the association with malignant tumors is extremely rare. To the best of our knowledge, we report the first case of sclerosing angiomatoid nodular transformation of the spleen associated with uterine clear cell carcinoma. CASE PRESENTATION: A 49-year-old Arabic woman presented to our institute with abdominal pain and distention. An abdominal computed tomographic scan was obtained, which showed a 14-cm uterine malignant tumor and a 4-cm isolated splenic nodule suggesting a metastatic lesion. The tumor was limited to the uterus but did not extend beyond. The patient underwent surgical treatment, and the histopathological examination of the resected uterine and splenic specimens disclosed invasive uterine clear cell carcinoma and sclerosing angiomatoid nodular transformation of the spleen, respectively. The patient had no signs of the disease 17 months after surgical treatment. CONCLUSIONS: Sclerosing angiomatoid nodular transformation of the spleen is a very rare benign disease with a misleading presentation when associated with a malignant tumor. Pathological assessment of the resected spleen is the only way to achieve the correct diagnosis.
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spelling pubmed-63042312019-01-03 Sclerosing angiomatoid nodular transformation of the spleen (SANT) in a patient with clear cell carcinoma of the uterus: a case report Efared, Boubacar Sidibé, Ibrahim S. Erregad, Fatimazahra Hammas, Nawal Chbani, Laila El Fatemi, Hinde J Med Case Rep Case Report BACKGROUND: Sclerosing angiomatoid nodular transformation of the spleen is a very rare benign vascular lesion recently described. Usually, sclerosing angiomatoid nodular transformation of the spleen is an incidental finding; the association with malignant tumors is extremely rare. To the best of our knowledge, we report the first case of sclerosing angiomatoid nodular transformation of the spleen associated with uterine clear cell carcinoma. CASE PRESENTATION: A 49-year-old Arabic woman presented to our institute with abdominal pain and distention. An abdominal computed tomographic scan was obtained, which showed a 14-cm uterine malignant tumor and a 4-cm isolated splenic nodule suggesting a metastatic lesion. The tumor was limited to the uterus but did not extend beyond. The patient underwent surgical treatment, and the histopathological examination of the resected uterine and splenic specimens disclosed invasive uterine clear cell carcinoma and sclerosing angiomatoid nodular transformation of the spleen, respectively. The patient had no signs of the disease 17 months after surgical treatment. CONCLUSIONS: Sclerosing angiomatoid nodular transformation of the spleen is a very rare benign disease with a misleading presentation when associated with a malignant tumor. Pathological assessment of the resected spleen is the only way to achieve the correct diagnosis. BioMed Central 2018-12-23 /pmc/articles/PMC6304231/ /pubmed/30579362 http://dx.doi.org/10.1186/s13256-018-1907-5 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Efared, Boubacar
Sidibé, Ibrahim S.
Erregad, Fatimazahra
Hammas, Nawal
Chbani, Laila
El Fatemi, Hinde
Sclerosing angiomatoid nodular transformation of the spleen (SANT) in a patient with clear cell carcinoma of the uterus: a case report
title Sclerosing angiomatoid nodular transformation of the spleen (SANT) in a patient with clear cell carcinoma of the uterus: a case report
title_full Sclerosing angiomatoid nodular transformation of the spleen (SANT) in a patient with clear cell carcinoma of the uterus: a case report
title_fullStr Sclerosing angiomatoid nodular transformation of the spleen (SANT) in a patient with clear cell carcinoma of the uterus: a case report
title_full_unstemmed Sclerosing angiomatoid nodular transformation of the spleen (SANT) in a patient with clear cell carcinoma of the uterus: a case report
title_short Sclerosing angiomatoid nodular transformation of the spleen (SANT) in a patient with clear cell carcinoma of the uterus: a case report
title_sort sclerosing angiomatoid nodular transformation of the spleen (sant) in a patient with clear cell carcinoma of the uterus: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304231/
https://www.ncbi.nlm.nih.gov/pubmed/30579362
http://dx.doi.org/10.1186/s13256-018-1907-5
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